201 polyether defoamers with propylene glycol or glycerin or other initiator with propylene oxide, ethylene oxide, etc. block polymerization or mass polymerization obtained, is characterized by non-toxic, efficient, no stain, moisture low, excellent chemical stability including food grade defoamers. Not applicable for most silicone defoamers defoaming industry, suppression needs bubbles. And it can be used as an emulsifier, emulsion, detergent and other products.